Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VCP P55072 valosin containing protein 1.00 0.469 0.923
TSPO P30536 translocator protein 2.7E-04 0.444 0.885
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808
SRRM2 Q9UQ35 serine/arginine repetitive matrix 2 1.00 0.564 0.692
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
SNCB Q16143 synuclein beta Transporter 6.8E-02 0.619 0.577
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
RBMS3 Q6XE24 RNA binding motif single stranded interacting protein 3 0.21 0.553 0.692
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923